Sapphire Princess South America Cruise From Los Angeles - November 16, 2025

20 Night Andes and South America

South America one way cruise departs from Los Angeles on Sunday November 16, 2025. The 20 day cruise ends with the arrival of Sapphire Princess in San Antonio on Saturday December 6, 2025. The Thanksgiving holiday (November 27, 2025) is during the cruise.

Ports of Call

November 23, 2025

Puntarenas, Costa Rica

Puntarenas is a port town on the Gulf of Nicoya on the west side of Costa Rica, about 50 miles west of San Jose.

More Puntarenas cruises...

November 25, 2025

Panama City, Panama

Panama City is the capital city of Panama with a population of over 450,000. It's on the Pacific coast at the eastern end of the Panama Canal.

More Panama City cruises...

Departure Port: World Cruise Center

Directions: Google Maps - Apple Maps

For the night before your cruise: Hotels near World Cruise Center

Sunrise Hotel San Pedro

525 S Harbor Blvd
0.5 miles from cruise port
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Crowne Plaza Los Angeles Harbor Hotel

601 S Palos Verdes St
0.6 miles from cruise port
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All Star Inn

411 South Pacific Avenue
0.7 miles from cruise port
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Best Western Plus San Pedro Hotel & Suites

111 South Gaffey Street
0.9 miles from cruise port
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Vagabond Inn San Pedro

215 S Gaffey St
0.9 miles from cruise port
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Americas Best Value Inn Rancho Palos Verdes

29601 South Western Avenue
1.8 miles from cruise port
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DoubleTree by Hilton San Pedro - Port of Los Angeles

2800 Via Cabrillo Marina
1.9 miles from cruise port
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Monterey Inn Hotel

233 N. Avalon Blvd
2.0 miles from cruise port
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Cruise Updates

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These destinations and more great places featured in our selections of the most interesting cruises in January 2026

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Start 2026 with a bang on one of these great cruises from LA scheduled to be at sea as the calendar changes from 2025 to 2026

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Get ready for a big cruise a year from now, with an exploration of the fjords of Scandinavia, a tour of the British Isles or a luxury transatlantic cruise.

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Lots of really long cruises from Fort Lauderdale on our list for next January, including several legs of world cruises to choose from

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Make that trip to the Panama Canal, see the fjords of South America or tour the Mediterranean this Christmas